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Antiproliferative agent-15

CAS No. 19819-18-2

Antiproliferative agent-15( —— )

Catalog No. M35822 CAS No. 19819-18-2

Antiproliferative agent-15 is a reagent with anticancer activity. Antiproliferative agent-15 showed antiproliferative activity against human colon cancer (HCT116 and HCT15) and brain cancer (LN-229 and GBM-10).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 202 Get Quote
10MG 301 Get Quote
25MG 462 Get Quote
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Biological Information

  • Product Name
    Antiproliferative agent-15
  • Note
    Research use only, not for human use.
  • Brief Description
    Antiproliferative agent-15 is a reagent with anticancer activity. Antiproliferative agent-15 showed antiproliferative activity against human colon cancer (HCT116 and HCT15) and brain cancer (LN-229 and GBM-10).
  • Description
    Antiproliferative agent-15 is an anticancer agent. Antiproliferative agent-15 shows antiproliferative activity against human colon (HCT116 and HCT15) and brain (LN-229 and GBM-10) cancer cell lines.
  • In Vitro
    Antiproliferative agent-15 (compound 6a) shows antiproliferative activity against human colon (HCT116 and HCT15), brain (LN-229 and GBM-10) cancer cell lines, with IC50 values of 8.3 μM, 4.8 μM, 18.3 μM, and 12 μM, respectively. However, Antiproliferative agent-15 has no active against ovarian (A2780) cancer cell lines and normal cell line (CHO).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    19819-18-2
  • Formula Weight
    282.36
  • Molecular Formula
    C16H14N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1C2=C(SC3=C2CCCC3)NC(=N1)C4=CC=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Haneen Amawi, et al. Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe. Eur J Med Chem. 2017 Sep 29;138:1053-1065.?
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